Reply to "colistin resistance during selective digestive tract decontamination is uncommon".
نویسندگان
چکیده
D. F. Zandstra, J. H. Rommes, M. A. de la Cal, L. Silvestri, N. Taylor, H. K. F. van Saene ‹Department of Intensive Care, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands; Intensive Care Unit, Gelre Ziekenhuizen, Apeldoorn, The Netherlands; Department of Intensive Care Medicine, Hospital Universitario de Getafe, Getafe, Spain; Department of Emergency, Unit of Anesthesia and Intensive Care, Presidio Ospedaliero, Gorizia, Italy; Institute of Ageing and Chronic Diseases, University of Liverpool, Liverpool, United Kingdom
منابع مشابه
Colistin and tobramycin resistance during long- term use of selective decontamination strategies in the intensive care unit: a post hoc analysis
INTRODUCTION Selective decontamination of the digestive tract (SDD) and selective oropharyngeal decontamination (SOD) have been shown to improve intensive care unit (ICU) patients' outcomes. The aim of this study was to determine the effects of long-term use of SDD and SOD on colistin and tobramycin resistance among gram-negative bacteria. METHODS We performed a post hoc analysis of two conse...
متن کاملSelective decontamination of the oropharynx and the digestive tract, and antimicrobial resistance: a 4 year ecological study in 38 intensive care units in the Netherlands.
OBJECTIVES Selective oropharyngeal decontamination (SOD) and selective decontamination of the digestive tract (SDD) are associated with improved outcomes among patients in intensive care units (ICUs), but uncertainty remains about their long-term effects on resistance levels. We determined trends in antibiotic resistance among Gram-negative bacteria in 38 Dutch ICUs using and not using SOD/SDD....
متن کاملEffect of a selective decontamination of the digestive tract regimen including parenteral cefepime on establishment of intestinal colonization with vancomycin-resistant Enterococcus spp. and Klebsiella pneumoniae in mice.
In mice, a selective decontamination of the digestive tract regimen consisting of orogastric tobramycin, polymyxin E, and amphotericin B in combination with subcutaneous cefepime inhibited gram-negative bacilli, including Klebsiella pneumoniae, and did not promote vancomycin-resistant Enterococcus spp. (VRE) colonization. However, concurrent administration of subcutaneous ampicillin-sulbactam r...
متن کاملMouthwash Is Great for Critically Ill Patients Decontamination of the Digestive Tract and Oropharnyx in ICU Patients
Background: Infectious complications remain a major concern in critically ill patients. Preventive measures are clearly better than treatment. Selective decontamination (SDD) of the upper digestive tract is one method that has had mixed results. Numerous questions exist as to whether or not gastrointestinal (GI) decontamination should be routine or not. Objective: To determine the effectiveness...
متن کاملSelective decontamination of the digestive tract: an update of the evidence
Selective decontamination of the digestive tract has been proven to prevent severe infections and to reduce mortality in critically ill patients. Historical arguments against its use, like the development of bacterial resistance and the absence of influence on mortality, have not been confirmed. Recent clinical trials designed to evaluate these variables and meta-analyses showed remarkable redu...
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 58 1 شماره
صفحات -
تاریخ انتشار 2014